Cardinals safety Tyvon Branch leaves the game with a knee injury that could be season-ending.
The Cardinals entered "Thursday Night Football" against the Seahawks with a healthy roster but left with multiple injuries that could be season-ending.
Left tackle D.J. Humphries is likely done for the year with an injury to his ACL, while safety Tyvon Branch (knee) and tight end Ifeanyi Momah (ankle) could also end up on injured reserve, coach Bruce Arians said.
Humphries missed four games earlier this season with a sprained knee but returned and was playing at a high level. He went down in the first quarter of the 22-16 loss when his right knee was rolled up on.
"It's just a shame," Arians said. "The guy was playing fantastic."
Branch hurt his knee while trying to defend Seahawks tight end Jimmy Graham on a 6-yard touchdown pass in the first quarter. He left the field without putting any pressure on his right leg. Branch had been one of the better safeties in the NFL through the first half of the season. Momah suffered his injury in the second half.
The Seahawks were hit hard by injuries as well. Star cornerback Richard Sherman tore his Achilles and will miss the rest of the season, coach Pete Carroll said. Left tackle Duane Brown left the game with an ankle injury in the second quarter and didn't return, and several other players were banged up, including Seattle quarterback Russell Wilson.
"Any time you play these guys, it's such a physical battle," wide receiver Larry Fitzgerald said. "Every time I looked up, it felt like trainers were running onto the field. It's just physical, no-holds-barred out there."
Some players felt like the quick turnaround from Sunday's games contributed to the bevy of injuries.
"This (expletive) should be illegal," Seahawks wide receiver Doug Baldwin said, via the Tacoma News Tribune. "It is not OK."
GRESHAM CATCHES ANOTHER TOUCHDOWN
Tight end
Jermaine Gresham has drawn praise for his run-blocking of late, and he's also become a big part of the passing game with Drew Stanton under center. Gresham has a touchdown in each of Stanton's starts, including a 14-yarder on a screen pass in the second quarter against the Seahawks.
Gresham, who had five catches for 64 yards and a score in the game, said he is growing a nice rapport with Stanton.
"I'm just playing my part in the offense and he's finding me," Gresham said.
OLSEN PIERRE GETS THE START
Defensive lineman Olsen Pierre received his first career start and was on the field regularly. He had a sack on the opening drive and finished with four tackles, including two for loss.
Pierre was bothered by an ankle injury a few weeks ago but is healthy now and has become one of the more effective players on the defensive front. He had a half-sack against the 49ers last week and has two-and-a-half on the season.
"I just grew mentally, working with guys like Frostee (Rucker) and (Corey Peters)," Pierre said. "I stay after, work the plays with them, work my technique with them. Mentally, I've grown a lot."
DEFERRING THE OPENING KICKOFF
Arians chose to defer instead of receive after winning the opening coin toss, a rarity in his coaching tenure.
The Cardinals' defense took the field first and forced a three-and-out to set the offense up with favorable field position at the Seattle 48, but running back Adrian Peterson fumbled on the first play and Seattle defensive end Sheldon Richardson recovered.
"After a great possession on the defensive side of the ball and great field position, to come out and give that ball up on the first play, it's unacceptable," Peterson said.
Images from the Week 10 "Thursday Night Football" affair

WR John Brown catches a pass

TE Jermaine Gresham scores on a touchdown reception

Seahawks DE Michael Bennett tackles Cardinals RB Adrian Peterson

Coach Bruce Arians

The Cardinals cheerleaders perform

QB Drew Stanton delivers a pass

S Antoine Bethea leads the defensive backs huddle

LB Haason Reddick rushes QB Russell Wilson

S Tyrann Mathieu before the game

Governor Doug Ducey (left) and team president Michael Bidwill

Seahawks TE Jimmy Graham catches a touchdown pass

RB Andre Ellington before the game

WR Larry Fitzgerald before the game

Cardinals cheerleaders perform

DL Olsen Pierre with a sack

The open roof

S Rudy Ford

Actress and singer Kristin Chenoweth performs the national anthem

Cardinals cheerleaders perform

The "Thursday Night Football" crew

Seahawks QB Russell Wilson

QB Drew Stanton before the game

Fans at the game

RB Andre Ellington punches through for a run

QB Drew Stanton with the throw

Cardinals head coach Bruce Arians

Seahawks CB Jeremy Lane (right) defends Cardinals WR John Brown

QB Drew Stanton moves to escape pressure

Seahawks TE Jimmy Graham makes the touchdown grab over Cardinals S Antoine Bethea

LB Chandler Jones works to get some pressure

Seahawks QB Russell Wilson plows through the Cardinals' defense

University of Phoenix Stadium on Salute to Service night

TE Jermaine Gresham scores a touchdown

Cardinals QB Drew Stanton (left) consults with Carson Palmer (center) and Blaine Gabbert (right) on the sideline

WR Larry Fitzgerald on the catch

TE Jermaine Gresham celebrates after scoring a touchdown

The Cardinals' offensive line prior to the snap

Service members during the halftime presentation

WR Jaron Brown goes up for the catch

QB Drew Stanton unloads

WR Jaron Brown bobbles the ball

Seahawks QB Russell Wilson escapes LB Chandler Jones (left) and S Tyrann Mathieu (center)

Seahawks S Kam Chancellor knocks the ball loose from Cardinals RB Adrian Peterson

Injured QB Carson Palmer watches from the sideline

Seahawks WR Paul Richardson makes the catch against Cardinals S Budda Baker

Drew Stanton looks for a flag

WR Larry Fitzgerald with the catch

Cardinals head coach Bruce Arians

QB Drew Stanton

K Phil Dawson after a made field goal

Seahawks WR makes the grab to lead to a 54-yard gain

John Brown with the catch and Seahawks CB Richard Sherman on the tackle

QB Drew Stanton throws the ball

Seahawks WR Doug Baldwin extends for the goal line but comes up short after a 54-yard gain

Russell Wilson (left) and Larry Fitzgerald (right) meet after the final whistle

Cardinals head coach Bruce Arians (left) greets Seahawks head coach Pete Carroll (right) after the game