SAN FRANCISCO 49ERS

Last time out: Giants 27, 49ers 23

Record: 2-8 overall, 0-3 in division

Snapshot: Giants quarterback Eli Manning hit Sterling Shepard on a 3-yard touchdown pass with 53 seconds left for the victory. San Francisco quarterback Nick Mullens wasn't as impressive in his second career start after a fantastic debut, completing 27-of-39 passes for 250 yards with a touchdown and two interceptions – albeit both picked passes were off deflections.

Notable: 49ers running back Matt Breida carried the ball 17 times for 101 yards and a touchdown. Manning threw for 188 yards and three touchdowns, two of which went to Odell Beckham, Jr. Both of Mullens' interceptions were picked off by Giants linebacker B.J. Goodson.

Quotable: "These are tough times and it takes everyone pulling together to help. These people are going to need support for a long time and I think we'll do whatever we can." – 49ers GM John Lynch, via the San Jose Mercury News, on bringing the Paradise High School football team to the game after its community was hit hard by the Camp Fire

Key Stat: 1. The number of sacks by the 49ers, one week after accumulating eight against the Raiders.

Next up: The 49ers host the Buccaneers in Week 11

SEATTLE SEAHAWKS

Last time out: Rams 36, Seahawks 31

Record: 4-5 overall, 1-2 in division

Snapshot: The Seahawks held a one-point lead heading into the fourth quarter, but the Rams scored 16 of the game's next 19 points to take control. Seattle quarterback Russell Wilson lost a fumble with under six minutes remaining and Los Angeles scored on a Brandin Cooks 9-yard run on the next play to cement the victory.

Notable: Seattle racked up 273 rushing yards, averaging 8.0 yards per carry, and still lost. Rashaad Penny had 12 carries for 108 yards and a touchdown, Wilson had 92 rushing yards and Mike Davis added 58. The Seattle defense gave up 456 yards of total offense and didn't get a takeaway.

Quotable: "There are times when you just need to take the ball away from them. You've got to tip some balls, you've got to knock balls out in the run game, and just take it away from them so that you can turn the game. That's as big a factor as anything. If we were plus today, we would have won." – Seahawks coach Pete Carroll, via Seahawks.com, on the turnover differential

Injury Update: Running back Chris Carson and guard D.J. Fluker missed the game but are expected back next week.

Next up: The Seahawks travel to play the Packers on "Thursday Night Football" in Week 11

LOS ANGELES RAMS

Last time out: Rams 36, Seahawks 31

Record: 9-1 overall, 4-0 in division

Snapshot: Jared Goff threw for 318 yards and two touchdowns while running back Todd Gurley added 120 rushing yards and a score as Los Angeles pulled away for the win. The Rams are tied with the Chiefs for the best record in the NFL and can clinch the NFC West next week with a victory and a Seattle loss.

Notable: Recently-acquired defensive end Dante Fowler had two penalties early on but had the crucial fourth-quarter strip-sack of Wilson to clinch the win. Cooks had 10 catches for 100 yards in addition to his touchdown run. Defensive tackle Aaron Donald had 2½ sacks and now has 12½ on the season.

Quotable: "We've all been affected by it. We had to move ourselves, so to win a game like this, a divisional game, we're trying to give people something to smile about." – Donald, via the Associated Press, on a heartbreaking week in Thousand Oaks which included a mass shooting and wildfires that made the players evacuate their homes

Injury Update: Wide receiver Cooper Kupp tore his ACL and is out for the season.

Next up: The Rams host the Kansas City Chiefs on "Monday Night Football" in Week 11