Cardinals RB Kenyan Drake takes QB Kyler Murray's floater on a screen pass for a speedy 21-yard pickup in the third quarter.

Watch the highlights from the Week 9 matchup between the San Francisco 49ers and Arizona Cardinals on Thursday Night Football.

Watch the best plays by newly acquired Cardinals RB Kenyan Drake in the Week 9 matchup against the San Francisco 49ers on Thursday Night Football.

Watch the best plays by Cardinals S Budda Baker in the Week 9 matchup against the San Francisco 49ers on Thursday Night Football.

Cardinals rookie QB Kyler Murray delivers to RB Kenyan Drake for a two-point conversion that puts the Cardinals within three late in the fourth quarter.

Cardinals WR Andy Isabella stuns the Niners with an 88-yard catch-and-run touchdown to make it 28-23 in the fourth quarter.

Cardinals QB Kyler Murray turns a read option play into a quick 21-yard sprint in the third quarter against the 49ers.

QB Kyler Murray's sidearm touchdown pass to WR KeeSean Johnson caps off a fast 83-yard drive for the Cardinals.

Cardinals LB Chandler Jones jumps on 49ers QB Jimmy Garoppolo's back for a sack in the third quarter.

Cardinals CB Tramaine Brock makes an impressive leap to knock down a pass from 49ers QB Jimmy Garoppolo in the second quarter.

Cardinals S Budda Baker makes a nice play to break up a pass intended for 49ers TE George Kittle.

RB Kenyan Drake dives for the pylon to convert a 4-yard touchdown on the Cardinals' opening drive against the 49ers.

On his first touch in a Cardinals uniform, RB Kenyan Drake carries the ball for a gain of 36 yards.